Now showing items 1-2 of 2

    • Article

      Drug assimilation in the tissue of European sea bass (Dicentrarchus labrax) fry delivered orally through bioencapsulation 

      RSJ Gapasin, HJ Nelis, M Chair & P Sorgeloos - Journal of Applied Ichthyology, 1996 - Wiley-Blackwell
      Assimilation levels of the antibacterials trimethoprim (TMP) and sulfamethoxazole (SMX) in sea bass (Dicentrarchus labrax) fry tissue administered orally were investigated. A 1:5 TMP and SMX combination incorporated in an oil emulsion (Selco) at 20 % and 40 % concentrations (w/w) were bioencapsulated in Artemia (Instar II) nauplii. Chemotherapeutics-loaded ('medicated) nauplii were fed to the sea bass fry and drug concentrations in the tissue were analysed by high-performance liquid chromatrography (HPLC). Fish fed 40 %'medicated Artemia assimilated significantly higher levels of chemotherapeutics compared with those fed 20 %'medicated' Artemia. Chemotherapeutics given at 40 % reached peak levels (19.3 μg TMP/g DW and 23.31 μg SMX/g DW) within 2 h while those at 20 % peaked (8.74 μg TMP/g DW and 6.73 fig SMX/g DW) after 5 h. TMP persisted in the tissues longer (up to 72 h) than SMX (12–16 h), suggesting a more efficient uptake and retention of the former and/or faster metabolism and elimination of the latter.
    • Article

      Vaccination of European sea bass fry through bioencapsulation of Artemia nauplii 

      M Chair, RSJ Gapasin, M Dehasque & P Sorgeloos - Aquaculture International, 1994 - European Aquaculture Society
      European sea bass (Dicentrarchus labrax) fry vaccinated orally via bioencapsulation in Artemia nauplii or by bath method exhibited better performance than control fish in terms of growth, food conversion and resistance to stress. The comparable survival between vaccinated and non-vaccinated animals suggests that vaccination methods are not stressful. The present study shows that oral vaccination can be used to enhance growth in fish fry.