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    • Book chapter

      Chapter 1. Detection of antibiotic residues in aquaculture products 

      JNP Chuan - In Laboratory manual of standardized methods for the analysis of pesticide and antibiotic residue in aquaculture products, 2004 - Aquaculture Department, Southeast Asian Fisheries Development Center
      Aquacultured animals are under constant threat from bio-aggressors such as viruses, bacteria, parasites and fungi. These organisms harm either spontaneously or through aquatic animal husbandry practices, and often both. Indeed, it is generally recognized that disease problems follow the development of techniques for animal production.

      Consequently, fish culture uses a variety of chemicals that represent potential threats to the health of the cultured animal, indigenous biota, and even humans. Chemicals employed in aquaculture include the following:

      - Drugs used to treat disease (chemical therapeutants)

      - Chemicals introduced through construction materials

      - Hormones used to alter reproductive viability, sex, and growth rates

      Of these, chemotherapeutic drugs are the most harmful. Chemotherapeutic treatments are initiated after clinical signs of a disease appear in a population of fish. Chemicals used in construction and hormones are not considered because they are relatively non-toxic.

      The use of chemical therapeutants obviously leads to the transit of drugs and to their persistence in products intended for human consumption. It also leads to the release of drugs or their metabolites to the aquatic environment. Hence the criticisms raised in the press against the use of chemotherapy in aquaculture, and the restrictive legislation set up in many countries under pressure of public opinion. It sometimes appears that people would believe that drug resistance of bacteria responsible for human infections originates exclusively, or almost exclusively, from consumption of animal products such as those provided by aquaculture.

      It should be noted that in addition to the chemicals that are deliberately used, fish raised in aquaculture are also susceptible to contamination via pesticides present in feed, agriculture run-off water, and sediments. The magnitude of human exposure to these sources has not yet been fully assessed and should be examined periodically in light of the growth and change in this sector of the seafood industry.
    • Book

      Laboratory manual of standardized methods for the analysis of pesticide and antibiotic residue in aquaculture products 

      IG Borlongan & JNP Chuan - 2004 - Aquaculture Department, Southeast Asian Fisheries Development Center
      The manual contains guidelines on the detection of antibiotic and pesticide residues in aquaculture products. Different methods for the analysis of the two chemicals are discussed. The manual is expected to benefit all those who are involved in the monitoring and enforcement aspects of chemical residue limits in aquaculture products in the region.