Show simple item record

dc.contributor.authorLio-Po, Gilda D.
dc.contributor.authorAlbright, Lawrence J.
dc.contributor.authorTraxler, Garth S.
dc.contributor.authorLeaño, Eduardo M.
dc.date.accessioned2014-01-16T07:41:08Z
dc.date.available2014-01-16T07:41:08Z
dc.date.issued2001
dc.identifier.citationLio-Po, G. D., Albright, L. J., Traxler, G. S., & Leaño, E. M. (2001). Pathogenicity of the epizootic ulcerative syndrome (EUS)-associated rhabdovirus to snakehead Ophicephalus striatus. Fish Pathology, 36(2), 57-66.en
dc.identifier.issn0388-788X
dc.identifier.urihttp://hdl.handle.net/10862/1905
dc.description.abstractThe rhabdoviruses isolated from EUS-affected snakeheads in the Philippines was tested for pathogenicity to healthy, naive snakehead Ophicephalus striatus fry, fingerlings and juveniles. Virus exposure of naive snakehead fry and fingerlings by bath at 20-22.5°C resulted in significant mortalities (p<0.01) with no apparent lesions. Naive snakehead juveniles when injected intramuscularly (IM) with the EUS-associated rhabdovirus at ambient water temperature (28-32°C) did not develop any lesion. However, similarly treated snakehead juveniles at 20-22.5°C developed dermal lesions 3-5 days following treatment. The lesions progressed from slight to moderately advanced lesions by days 10-12 but not to deep ulcers as exhibited by naturally EUS-affected snakeheads. Mean mortalities were higher in the virus-injected fish (72%) compared to those in controls (33%). Moreover, the virus was reisolated from fish in the 20-22.5°C treatment but not from fish in the 28-32°C treatment. Virus from infected tissue filtrate and the virus passaged 3 or 4 times induced similar dermal lesions if the rhabdovirus concentration was 103 TCID50/fish or higher. When administered orally, by bath, by intraperitoneal (IP), IM and subdermal injections to snakehead juveniles, only the latter two viral routes induced dermal lesions. However, IP injection of the rhabdovirus caused 75% mortalities but none in control fish. The results demonstrate the pathogenicity of the rhabdovirus isolates to naive snakeheads at low (20-22.5°C) rearing water temperatures.en
dc.description.sponsorshipResearch funding was provided by the Aquaculture Department, Southeast Asian Fisheries Development Center and the International Development Research Centre (IDRC) of Canada (Fish Microbiology Project 3-P-88-1053-02).en
dc.language.isoenen
dc.publisherJapanese Society of Fish Pathologyen
dc.subjectFish rhabdovirusesen
dc.subjectOphicephalus striatusen
dc.subjectSnakeheaden
dc.subjectEpizootic ulcerative syndromeen
dc.subjectEUSen
dc.subjectPathogenicityen
dc.titlePathogenicity of the epizootic ulcerative syndrome (EUS)-associated rhabdovirus to snakehead Ophicephalus striatusen
dc.typeArticleen
dc.identifier.doi10.3147/jsfp.36.57
dc.citation.volume36
dc.citation.issue2
dc.citation.spage57
dc.citation.epage66
dc.citation.journalTitleFish Pathologyen
seafdecaqd.library.callnumberVF SJ 0716
seafdecaqd.databank.controlnumber2001-08
dc.subject.asfaFish diseasesen
dc.subject.asfaPathogensen


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record