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dc.contributor.authorTendencia, Eleonor
dc.coverage.spatialPhilippinesen
dc.date.accessioned2022-09-13T01:22:08Z
dc.date.available2022-09-13T01:22:08Z
dc.date.issued2022-09-03
dc.identifier.citationTendencia, E. A. (2022). Accumulation and depletion of oxytetracycline (OTC) and oxolinic acid (OXA) in Pompano, Trachinotus blochii. Bulletin of the European Association of Fish Pathologists. https://doi.org/10.48045/001c.37646en
dc.identifier.issn0108-0288
dc.identifier.urihttp://hdl.handle.net/10862/6362
dc.description.abstractAccumulation and depletion including withdrawal period for oxytetracycline (OTC) and oxolinic acid (OXA) in pompano (Trachinotus blochii) were determined following oral administration. Pompano were cultured in 250-L fiberglass tanks in a flow-through system provided with aeration. Observed average temperature was 30°C; salinity was 30 ppt. Fish were starved for 2 days then fed with OTC medicated diet (75mg/kg fish/day) or OXA medicated diet (30 mg/kg fish/day) 3 times a day for 10 successive days at 2% body weight and thereafter switched to regular diet for 45 days. Muscle and blood samples were taken at regular intervals during and after cessation of medication. OTC residues in the muscle and blood were analysed using the high performance liquid chromatography (HPLC). Peak OTC accumulation was observed at day 10 of treatment. Higher OTC accumulation was observed in the muscle (0.88+0.27 µg/g) than in the blood (0.3+0.09 µg/ml). OXA accumulation peaked on day 5 of treatment; higher OXA accumulation was observed in the muscle (0.11+0.06 µg/g) compared to blood (0.005+0.0001 ug/ml). Withdrawal period at 30°C for OTC in pompano muscle was 19 days (570 degree-days) and 17 days (510 degree-days) in the blood. For OXA, the withdrawal period in pompano muscle and blood at 30°C temperature was 3 days (90 degree-days).en
dc.description.sponsorshipThe study was funded by the Government of Japan under the Trust Fund (GoJ TF 4) granted to SEAFDEC AQD under study code FH-01-F2014T.en
dc.language.isoenen
dc.publisherEuropean Association of Fish Pathologistsen
dc.relation.urihttps://eafpbulletin.scholasticahq.com/article/37646.pdfen
dc.subjectpompanosen
dc.subjectTrachinotus blochiien
dc.subjectPhilippinesen
dc.subjectoral administrationen
dc.titleAccumulation and depletion of oxytetracycline (OTC) and oxolinic acid (OXA) in Pompano, Trachinotus blochiien
dc.typeArticleen
dc.identifier.doi10.48045/001c.37646
dc.citation.journalTitleBulletin of the European Association of Fish Pathologistsen
dc.subject.asfaaccumulationen
dc.subject.asfamusclesen
dc.subject.asfablooden
dc.subject.asfachromatographyen
dc.subject.asfaantibioticsen
dc.subject.asfafeedsen
dc.subject.asfaacclimatizationen
dc.subject.scientificNameTrachinotus blochiien
local.subjectoxytetracyclineen
local.subjectoxolinic aciden
local.subjectpompanoen
local.subjectwithdrawal perioden


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  • Journal Articles [1221]
    These papers were contributed by Department staff to various national and international journals.

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