Growth regulation by insulin-like growth factor-I in fish
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Abstract
Insulin-like growth factor-I (IGF-I) is a mitogenic polypeptide that plays an essential role in the regulation of development and somatic growth of vertebrates, mainly by mediating growth hormone actions. It has clearly been established that the structure of IGF-I and its biological function has been highly conserved among vertebrates. In this paper, we review the recent developments in the molecular, biochemical, and physiological properties of IGF-I in fish.
Suggested Citation
Moriyama, S., Ayson, F. G., & Kawauchi, H. (2000). Growth regulation by insulin-like growth factor-I in fish. Bioscience, Biotechnology and Biochemistry , 64(8), 1553-1562. https://doi.org/10.1271/bbb.64.1553
Type
Article; ReviewISSN
0916-8451Collections
- Journal Articles [1278]
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(Aquaculture Department, Southeast Asian Fisheries Development Center, 1976)Presented in this paper are the recommendations on current and future research activities for the biological investigations on milkfish (Chanos chanos). Included were the bahavior and bio-ecology of milkfish in the wild. It also tackled the protocols in transporting broodstocks. -
Larval and early juvenile development of silver therapon, Leiopotherapon plumbeus (Actinopterygii: Perciformes: Terapontidae), reared in mesocosms
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; ; ; Garcia, Luis Maria (Szczecińskie Towarzystwo Naukowe, 2017)
The silver therapon, Leiopotherapon plumbeus (Kner, 1864), is an endemic and economically important freshwater food fish in the Philippines. The natural populations of this species have been declining during the past years, mainly due to intense fishing pressure, habitat degradation, and introduction of invasive alien species. At present, it is considered a target species for domestication and conservation efforts. Despite several attempts of artificial reproduction and larval rearing, little is known on larval and early juvenile development of silver therapon. The presently reported study was therefore intended to fill this gap in the knowledge by determining the growth and describing body proportions, pigmentation, and fin formation of this fish. Newly hatched larvae were reared in mesocosm tanks at a mean temperature of 29.5°C. Larvae up to 30 days after hatching were sampled at irregular intervals and preserved in 5% buffered formalin. Early development stages for 245 preserved specimens were described in detail with reference to changes in morphology, growth and body proportions, pigmentation, and fin formation. Five developmental stages of silver therapon were identified: yolk sac larva (1.88 mm TL), preflexion (2.51 mm TL), notochord flexion (4.50-8.27 mm TL), postflexion larva (6.90-12.21 mm TL), and early juvenile (>13.40 mm TL). Growth was isometric for eye diameter and gape size whereas positive allometry was observed for body depth, head length, and preanal length. Some body proportions showed abrupt changes from preflexion to postflexion larvae before it stabilized during the early juvenile stage. Pigmentation in the form of stellate and punctate melanophores increased with developmental stage, with larvae becoming heavily pigmented from postflexion to early juvenile stage. These morphological changes, together with the full complement of fin rays and squamation observed in specimens larger than 13.4 mm TL, suggest the attainment of the juvenile stage of this species. These morphological changes may explain the food and feeding habits during the early life stages of silver therapon which is critical to their survival and recruitment in the wild and in a mesocosm hatchery environment. -
Role of growth hormone in the adaptation to sea water of juveline brown trout, (Salmo trutta)
(Aquaculture Department, Southeast Asian Fisheries Development Center, 1996)The first part of the study investigates the ability of ovine growth hormone (oGH) to enhance the hypo-osmoregulatory and growth performance of juvenile brown trout after exposure to sea water (SW). Three groups of fish were either intraperitoneally implanted with cholesterol pellet (sham) or with a cholesterol pellet containing 250 µg oGH (treated) or not implanted (control). While still in fresh water (FW), gill Na+/K+ATPase activity of the oGH-treated group was four times higher than that of sham and control groups. Exposure to SW resulted to dramatic increases in plasma electrolyte levels of the sham and control groups, whereas the oGH-treated group showed only minor perturbations in plasma electrolyte concentrations. Further increases in gill Na+/K+ ATPase activity were observed in the oGH-treated group after SW exposure, while in the sham and control, a lag time of seven days was needed before gill ATPase activity started to increase. Additionally, by the end of the experiment, oGH-treated fish were significantly larger than non-treated ones. The second part of the study examines the time course of changes in plasma GH levels and GH free binding sites and affinity of the organs involved in osmoregulation in juvenile brown trout kept in FW or exposed to SW. Plasma GH levels increased significantly one day after SW exposure, reaching a peak on the 14th day. Concomitantly, GH free binding sites in the gills and liver decreased significantly in trout exposed to SW but remained unchanged in trout kept in FW. Reduction in GH free binding sites in SW-exposed trout indicates occupation of the gill and liver GH receptor by GH during the course of SW adaptation which may point to a direct role of GH on gill and liver physiology during hypo-osmoregulation. The second part of the study examines the time course of changes in plasma GH levels and GH free binding sites and affinity of the organs involved in osmoregulation in juvenile brown trout kept in FW or exposed to SW. Plasma GH levels increased significantly one day after SW exposure, reaching a peak on the 14th day. Concomitantly, GH free binding sites in the gills and liver decreased significantly in trout exposed to SW but remained unchanged in trout kept in FW. Reduction in GH free binding sites in SW-exposed trout indicates occupation of the gill and liver GH receptor by GH during the course of SW adaptation which may point to a direct role of GH on gill and liver physiology during hypo-osmoregulation.
