Pathogenicity of the epizootic ulcerative syndrome (EUS)-associated rhabdovirus to snakehead Ophicephalus striatus
MetadataShow full item record
Cited times in Scopus
The rhabdoviruses isolated from EUS-affected snakeheads in the Philippines was tested for pathogenicity to healthy, naive snakehead Ophicephalus striatus fry, fingerlings and juveniles. Virus exposure of naive snakehead fry and fingerlings by bath at 20-22.5°C resulted in significant mortalities (p<0.01) with no apparent lesions. Naive snakehead juveniles when injected intramuscularly (IM) with the EUS-associated rhabdovirus at ambient water temperature (28-32°C) did not develop any lesion. However, similarly treated snakehead juveniles at 20-22.5°C developed dermal lesions 3-5 days following treatment. The lesions progressed from slight to moderately advanced lesions by days 10-12 but not to deep ulcers as exhibited by naturally EUS-affected snakeheads. Mean mortalities were higher in the virus-injected fish (72%) compared to those in controls (33%). Moreover, the virus was reisolated from fish in the 20-22.5°C treatment but not from fish in the 28-32°C treatment. Virus from infected tissue filtrate and the virus passaged 3 or 4 times induced similar dermal lesions if the rhabdovirus concentration was 103 TCID50/fish or higher. When administered orally, by bath, by intraperitoneal (IP), IM and subdermal injections to snakehead juveniles, only the latter two viral routes induced dermal lesions. However, IP injection of the rhabdovirus caused 75% mortalities but none in control fish. The results demonstrate the pathogenicity of the rhabdovirus isolates to naive snakeheads at low (20-22.5°C) rearing water temperatures.
Lio-Po, G. D., Albright, L. J., Traxler, G. S., & Leaño, E. M. (2001). Pathogenicity of the epizootic ulcerative syndrome (EUS)-associated rhabdovirus to snakehead Ophicephalus striatus.
Fish Pathology, 36(2), 57-66. https://doi.org/10.3147/jsfp.36.57
- Journal Articles 
Showing items related by title, author, creator and subject.
Characterization of a virus obtained from snakeheads Ophicephalus striatus with epizootic ulcerative syndrome (EUS) in the Philippines Lio-Po, Gilda D.; Traxler, Garth S.; Albright, Lawrence J.; Leaño, Eduardo M. (Inter Research, 2000)This is the first report of the isolation and characterization of a fish virus from the Philippines. The virus was isolated using snakehead spleen cells (SHS) from severely lesioned epizootic ulcerative syndrome (EUS)-affected ...
Experimental induction of lesions in snakeheads (Ophicephalus striatus) and catfish (Clarias batrachus) with Aeromonas hydrophila, Aquaspirillum sp., Pseudomonas sp. and Streptococcus sp. Lio-Po, Gilda D.; Albright, L. J.; Michel, C.; Leaño, E. M. (Wiley-Blackwell, 1998)Isolates of Aquaspirilluni sp., Pseudomonas sp., and Streptococcus sp. recovered from epizootic ulcerative syndrome (EUS)-affected snakeheads (Ophicephalus striatus) in Thailand as well as an isolate of Aeromonas hydrophila ...
Lio-Po, Gilda D.; Albright, Lawrence J.; Leaño, Eduardo M. (American Fisheries Society, 1996)Aeromonas hydrophila, isolated from chevron snakehead Ophicephalus (=Channa) striatus affected with epizootic ulcerative syndrome (EUS), was injected intramuscularly into healthy walking catfish Clarias batrachus at varying ...